METABOLIC DISORDERS OF FOLATE CASCADE PROCESS

Kudratova Z. E.; Daminov F. A.; Tursunova M. E.; Khaidarova Sh.

METABOLIC DISORDERS OF FOLATE CASCADE PROCESS

Authors

Kudratova Z. E. PhD, Acting Assistant Professor of Clinical Laboratory Diagnostics Department with a Course of Clinical Laboratory Diagnostics of PGD SamSMU
Daminov F. A. PhD, Associate Professor, Head of the Department of Clinical Laboratory Diagnostics with a Course of Clinical Laboratory Diagnostics of PGD SamSMU
Tursunova M. E. Master Degree of the Department Endocrinology SamSMU
Khaidarova Sh. Clinical Resident of the Department of Clinical Laboratory Diagnostics with a Course of Clinical Laboratory Diagnostics of PGD SamSMU

Keywords:

folate cycle, vitamin B12, methionine synthases, DNA and RNA.

Abstract

The folate cycle is a cascade process of converting folic acid into a derivative available for absorption by the body, 5-methyltetrahydrofolate. The process is controlled by the enzyme methylenetetrahydrofolate reductase (MTHFR). Folate metabolism is a source of one-carbon fragments (methyl group -CH3) for vital cellular processes: purine nucleotide biosynthesis and conversion of uridine monophosphate into thymidylate; DNA and RNA methylation.

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Published

2024-05-24

How to Cite

Kudratova Z. E., Daminov F. A., Tursunova M. E., & Khaidarova Sh. (2024). METABOLIC DISORDERS OF FOLATE CASCADE PROCESS. Web of Discoveries: Journal of Analysis and Inventions, 2(5), 101–104. Retrieved from http://webofjournals.com/index.php/3/article/view/1394