UNIQUE PRINCIPLES OF COMPLEMENT BINDING REACTION

Umarova Tamila Abdufattoevna; Kudratova Zebo Erkinovna; Xodjimetova Ruxshona; Raxmatova Madina

UNIQUE PRINCIPLES OF COMPLEMENT BINDING REACTION

Authors

Umarova Tamila Abdufattoevna Assistant of the Department of Clinical Laboratory Diagnostics with a course of clinical and laboratory diagnostics PGD
Kudratova Zebo Erkinovna PhD, Associate Professor of the Department of Clinical Laboratory Diagnostics with a Course of Clinical and Laboratory Diagnostics PGD
Xodjimetova Ruxshona Cadet (Laboratory Doctor) of the Department of Clinical Laboratory Diagnostics with a Course of Clinical and Laboratory Diagnostics PGD
Raxmatova Madina Cadet (Laboratory Doctor) of the Department of Clinical Laboratory Diagnostics with a Course of Clinical and Laboratory Diagnostics PGD; Samarkand State Medical University, Samarkand, Uzbekistan

Keywords:

antibodies, antigens, specificity, immune complex, complement system;

Abstract

The unique ability of complement to bind specifically to antigen-antibody complexes of different nature has been utilised in the complement binding reaction (CBR) proposed in 1901 by J. Borde and O. Jangou. The particular advantage of the complement binding reaction is that the nature of the antigen involved (corpuscular or soluble) is irrelevant, since complement binds to the Fc-fragment of any IgG and IgM antibody, irrespective of its antigenic specificity.

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Published

2024-10-04

How to Cite

Umarova Tamila Abdufattoevna, Kudratova Zebo Erkinovna, Xodjimetova Ruxshona, & Raxmatova Madina. (2024). UNIQUE PRINCIPLES OF COMPLEMENT BINDING REACTION. Web of Medicine: Journal of Medicine, Practice and Nursing, 2(10), 22–25. Retrieved from http://webofjournals.com/index.php/5/article/view/1843