THE ROLE OF LIVER FUNCTION TESTS IN PEDIATRIC HEPATIC DISEASES

Mamanazarova Jasmina; Isomadinova Lola Kamolidinovna; Yulayeva Irina Andreevna

Authors

Mamanazarova Jasmina Сadet of the Department of Clinical and Laboratory Diagnostics with a Course of PGD Clinical and Laboratory Diagnostics of Samarkand State University Samarkand, Uzbekistan
Isomadinova Lola Kamolidinovna Assistant of the Department of Clinical and Laboratory Diagnostics with a Course of PGD Clinical and Laboratory Diagnostics of Samarkand State University Samarkand, Uzbekistan
Yulayeva Irina Andreevna Assistant of the Department of Clinical and Laboratory Diagnostics with a Course of PGD Clinical and Laboratory Diagnostics of Samarkand State University Samarkand, Uzbekistan

Keywords:

Liver function tests, pediatrics, ALT, AST, ALP, GGT, bilirubin, albumin, liver diseases, hepatitis, biliary atresia, cirrhosis.

Abstract

Liver function tests (LFTs) are a critical part of pediatric diagnostic workups for assessing liver health and identifying liver diseases. These tests measure various enzymes, proteins, and substances produced by or processed in the liver, offering insight into liver function, damage, and disease progression. This article reviews the importance of liver function tests in children, including common markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), bilirubin, and albumin. The article also explores how these tests aid in the diagnosis of pediatric liver diseases, such as hepatitis, biliary atresia, cirrhosis, and metabolic liver disorders.