FACTORS AFFECTING LUCIFERASE-BASED BIOLUMINESCENT IMAGING: A STUDY OF PRECLINICAL BREAST CANCER MODELS

Authors

  • Shaynazarov Muhammad Fayzullaevich
  • Jamshidov Farhod Jamshid o`g`li Scientific Advisor: Sattorov Yorqin Karimovich Tashkent Medical Academy, Tashkent, Republic of Uzbekistan

Keywords:

Bioluminescent imaging, luciferase, breast cancer, preclinical models, efflux mechanisms.

Abstract

Bioluminescent imaging (BLI) is a non-invasive and sensitive method for tracking tumor growth, based on the luciferase reaction. It is used to assess tumor size and evaluate treatment efficacy. However, the accuracy of BLI is influenced by factors such as substrate distribution, transport, and clearance. This study analyzes the key factors that impact the effectiveness of BLI in preclinical models of breast cancer.

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Published

2025-05-21

Issue

Vol. 3 No. 5 (2025): WOM

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

FACTORS AFFECTING LUCIFERASE-BASED BIOLUMINESCENT IMAGING: A STUDY OF PRECLINICAL BREAST CANCER MODELS. (2025). Web of Medicine: Journal of Medicine, Practice and Nursing , 3(5), 366-368. https://webofjournals.com/index.php/5/article/view/4280