SKLETAL MUSCLE RELAXANTS. PERIPHERALLY ACTING SKLETAL MUSCLE RELAXAXANTS: NEUROMUSCULAR BLOCKERS AND SYNTHETIC COMPETITIVE BLOCKERS
Keywords:
curare, alkaloid, nicotinic receptor, tubocurarine, acetylcholine, anticholinesterase, histamine, respiratory paralysis.Abstract
Skeletal muscle relaxants (SMRs) are drugs that reduce the muscle tone either by acting peripherally at the neuromuscular junction (neuromuscular blockers) or centrally in the cerebrospinal axis or directly on the contractile mechanism. They reduce the spasticity in a variety of neurological conditions and are also useful in surgeries.
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