COMPARATIVE EFFECT OF “AS LUPINUS” AND GLYCORASMULIN ON ATP-DEPENDENT POTASSIUM CHANNEL ACTIVITY IN SQUID LIVER MITOCHONDRIA IN ALLOXAN DIABETES

Authors

  • Ibragim Rakhmanovich Askarov Professor, Department of Chemistry, Andijan State University, Doctor of Science
  • Charosxon Sanjarbek qizi Abdujabborova Fergana Medical Institute of Public Health. Teacher of the Department of Traditional Medicine and Pharmacology

Keywords:

Japanese safflower (lat. Styphnolobium japo'nicum), Lupine (lat. Lupus), glucose, insulin, MDA, mPTP, mitoKATF, LPO, Alloxan (

Abstract

In this article, when examining the antioxidant activity of a mixture of Japanese safflower (lat. Styphnolobium japo'nicum) and Lupin (lat. Lupus) plants found in Uzbekistan, high antioxidant activity was detected in a 1:1 ratio, so we created a biological food supplement for the treatment of diabetes from this 1:1 ratio and named it “As Lupinus”. In order to analyze the biological activity of the “As Lupinus” food supplement, the effect of the “As Lupinus” food supplement on the amount of glucose and insulin in rat blood plasma in alloxan diabetes was studied at the Tashkent Institute of Bioorganic Chemistry using the in vivo method. The aim of the study was to conduct preclinical testing of the biological activity of this “As Lupinus” food supplement and to create and apply it in practice.

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Published

2025-05-31

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Articles

How to Cite

COMPARATIVE EFFECT OF “AS LUPINUS” AND GLYCORASMULIN ON ATP-DEPENDENT POTASSIUM CHANNEL ACTIVITY IN SQUID LIVER MITOCHONDRIA IN ALLOXAN DIABETES. (2025). Web of Medicine: Journal of Medicine, Practice and Nursing , 3(5), 705-708. https://webofjournals.com/index.php/5/article/view/4438