KALLIKREIN-KININ SYSTEM, PROTEASE INHIBITORS FOR CHRONIC GLOMERULONEPHRITIS

Authors

  • Tursunbaev A.K.
  • Karimova N.A..

Keywords:

Kallikrein-kinin system, glomerulonephritis, children.

Abstract

Objective: to determine the state of the kallikrein-kinin system and protease inhibitors in various clinical forms of glomerulonephritis in children. Materials and methods of the study. To solve the set tasks, 85 children with glomerulonephritis aged 3 to 15 years will be examined. Results and discussion. Patients of the first group showed significant activation of the KKS. The activity of K exceeded the norm by 1.7 times (p<0.001). The level of PC was reduced by 1.1 times (p<0.01). Conclusions: the state of the KKS has certain features in various clinical forms of CGN: mild CGN is characterized by pronounced activation of the KKS controlled by the protease system, probably caused by immune inflammation.

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Published

2025-06-11

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Section

Articles

How to Cite

KALLIKREIN-KININ SYSTEM, PROTEASE INHIBITORS FOR CHRONIC GLOMERULONEPHRITIS. (2025). Web of Medicine: Journal of Medicine, Practice and Nursing , 3(6), 119-123. https://webofjournals.com/index.php/5/article/view/4560