CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF OPPORTUNISTIC INFECTIONS IN IMMUNOCOMPROMISED INDIVIDUALS

Authors

  • Sattorov Sirojiddin Adhamjon oʻgʻli Assistant of Fergana Medical Institute of Public Health

Keywords:

immunosuppression, epidemiology, incidence, pathogenesis, mortality, candidiasis, aspergillosis, cytomegalovirus, pneumocystis, tuberculosis, transplantation, chemotherapy, prophylaxis, diagnostics, surveillance

Abstract

Opportunistic infections represent a significant clinical challenge in immunocompromised populations, with mortality rates reaching 35-40% in severely affected individuals. This study examines the epidemiological patterns and clinical manifestations of opportunistic infections across 847 immunocompromised patients over a 36-month period. Fungal infections predominated at 42.3%, followed by viral (31.7%) and bacterial (26.0%) etiologies. HIV-positive patients demonstrated the highest infection burden (68.4%), while solid organ transplant recipients showed distinct pathogen profiles. These findings underscore the necessity for targeted prophylactic strategies and improved diagnostic protocols in high-risk populations.

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Published

2025-12-31

Issue

Vol. 3 No. 12 (2025): WOM

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF OPPORTUNISTIC INFECTIONS IN IMMUNOCOMPROMISED INDIVIDUALS. (2025). Web of Medicine: Journal of Medicine, Practice and Nursing , 3(12), 484-490. https://webofjournals.com/index.php/5/article/view/5772