HEART RATE VARIABILITY AS A MARKER OF AUTONOMIC MALADAPTATION IN PREGNANT WOMEN WITH THREATENED MISCARRIAGE

Abstract

The aim of the study was to assess heart rate variability (HRV) in pregnant women with threatened miscarriage (TM) as a marker of autonomic maladaptation and a predictor of adverse gestational outcomes. Seventy-two pregnant women at 8–22 weeks of gestation were examined: 42 patients with clinical signs of TM and 30 women with physiological pregnancy. HRV was recorded by 5-minute cardiointervalography. Patients with TM demonstrated a significant decrease in SDNN, RMSSD, HF, and pNN50 with a simultaneous increase in the LF/HF index, reflecting predominance of sympathetic activation and suppression of vagal control. HRV may be considered an accessible and informative method for early identification of pregnant women at high risk.