HISTOCHEMICAL CHARACTERISTICS OF PLACENTAL TISSUE IN WOMEN WITH CARDIAC DEFECTS

Authors

  • Isroilova Gulsanam Muxtorjon qizi Assistant, Department of Obstetrics and Gynecology Fergana Medical Institute of Public Health

Keywords:

Cardiac defects, placental histochemistry, syncytiotrophoblast, fibrinoid necrosis, PAS-reaction, glycogen depletion, Alcian Blue staining, acid mucopolysaccharides, fetoplacental insufficiency, villous edema, stromal fibrosis, Van Gieson staining, placental ischemia, basement membrane, perinatology.

Abstract

This study examines histochemical alterations in placental tissue from women with congenital and acquired cardiac defects compared to healthy controls. Applying PAS-reaction, Alcian Blue, Van Gieson, Sudan III, and hematoxylin-eosin staining to 60 specimens, we identified significant reduction in trophoblast glycogen, increased fibrinoid deposition, basement membrane thickening, stromal fibrosis, and lipid accumulation, confirming measurable hypoxic placental injury.

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Published

2026-05-20

Issue

Vol. 4 No. 5 (2026): WOM

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

HISTOCHEMICAL CHARACTERISTICS OF PLACENTAL TISSUE IN WOMEN WITH CARDIAC DEFECTS. (2026). Web of Medicine: Journal of Medicine, Practice and Nursing , 4(5), 185-189. https://webofjournals.com/index.php/5/article/view/6424