IMMUNIZATION RULES FOR PREMATURE NEWBORNS

Maxmudova Shoxida Ergashevna

Authors

Maxmudova Shoxida Ergashevna So‘zangaron Abu Ali ibn Sino Public Health College Department of “Nursing Care” Lecturer of the Subject “Community Nursing”

Keywords:

Premature newborns, immunization, neonatal vaccination schedule, immune system immaturity, hepatitis B vaccine, WHO guidelines, CDC recommendations, neonatal care, vaccine safety.

Abstract

Immunization of premature newborns is a critical component of neonatal healthcare aimed at protecting this high-risk group from severe infectious diseases. Due to the immaturity of their immune system, premature infants are more vulnerable to infections; therefore, vaccination schedules must be carefully adapted based on gestational age, birth weight, and clinical stability rather than chronological age alone. Modern clinical guidelines from the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) emphasize that most routine vaccines should be administered to premature infants according to the same chronological schedule as full-term infants, provided the newborn is clinically stable. Special attention is required for extremely low birth weight infants, particularly regarding hepatitis B vaccination, where maternal HBsAg status significantly influences timing and dosing strategy.