LABORATORY SIGNIFICANCE OF SYSTEMIC INFLAMMATORY MARKERS IN VARIOUS FORMS OF BRUCELLOSIS AND OPTIMIZATION OF TREATMENT

Abstract

Human brucellosis, an endemic zoonosis triggered by intracellular pathogens of the genus Brucella, continues to pose severe clinical challenges due to its extensive systemic polymorphism and a high propensity for chronic progression. Conventional serological and bacteriological assays confirm target exposure but fail to map real-time immunological stress or track localized tissue damage during therapeutic courses. Identifying precise biochemical indicators is therefore vital to improve clinical staging and avoid long-term disability.