DEVELOPMENT AND GENETIC VALIDATION OF THE NCCAHSCREENF SCREENING SCALE FOR PREVENTION AND EARLY DIAGNOSIS OF NONCLASSICAL CONGENITAL ADRENAL CORTEX DYSFUNCTION IN WOMEN OF FERTILE AGE

Authors

  • Usmonov Akmaljon Axmadjonovich Endocrinologist, Davr Clinic Affiliated with “Fargʻona tibbiyot fayzi” LLC

Keywords:

21-hydroxylase deficiency, CYP21A2 mutation, 17-hydroxyprogesterone, hyperandrogenism, cosyntropin stimulation test, oligomenorrhea, hirsutism, anovulation, adrenal steroidogenesis, PCOS differential diagnosis, ROC analysis, androstenedione, adrenarche, glucocorticoid insufficiency, endocrine screening.

Abstract

Nonclassical congenital adrenal hyperplasia (NCCAH) remains systematically underdiagnosed in women of fertile age due to phenotypic overlap with polycystic ovary syndrome. This study presents development and genetic validation of the NCCAHSCREENF clinical screening scale, integrating hormonal, dermatological, reproductive, and molecular criteria to enhance early diagnostic precision in routine endocrinological and gynecological practice.

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Published

2026-05-13

Issue

Vol. 4 No. 5 (2026): WOM

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

DEVELOPMENT AND GENETIC VALIDATION OF THE NCCAHSCREENF SCREENING SCALE FOR PREVENTION AND EARLY DIAGNOSIS OF NONCLASSICAL CONGENITAL ADRENAL CORTEX DYSFUNCTION IN WOMEN OF FERTILE AGE. (2026). Web of Medicine: Journal of Medicine, Practice and Nursing , 4(5), 141-146. https://webofjournals.com/index.php/5/article/view/6380