CLINICAL AND PROGNOSTIC MARKERS OF CARDIORENAL SYNDROME PROGRESSION AND THEIR ROLE IN PERSONALIZED TREATMENT

Abstract

Cardiorenal syndrome is a relevant problem in modern cardiology and nephrology, associated with the mutual deterioration of cardiac and renal function. This article discusses clinical and prognostic markers of cardiorenal syndrome progression, including reduced estimated glomerular filtration rate, elevated NT-proBNP levels, albuminuria, type 2 diabetes mellitus, and signs of venous congestion. It is shown that a comprehensive assessment of these parameters makes it possible to identify high-risk patients and justify a personalized approach to treatment. Individualized therapy contributes to reducing the frequency of heart failure decompensation and slowing the progression of renal dysfunction.