CIPROFLOXACIN: CHEMICAL STRUCTURE, MECHANISM OF ACTION, PHARMACOKINETICS AND CLINICAL SIGNIFICANCE

Authors

  • Kurbanova M. A. Associate Professor, Department of Medical and Biological Chemistry No. 1, Tashkent State Medical University
  • Rustamov Shukhratjon Shavkatjonovich Student, Faculty of Medicine No. 1, Tashkent State Medical University

Keywords:

Ciprofloxacin, fluoroquinolones, medicinal chemistry, antibiotics, DNA gyrase, topoisomerase IV, pharmacokinetics, resistance, adverse effects.

Abstract

This article reviews ciprofloxacin, a synthetic antibacterial agent belonging to the fluoroquinolone class. Its chemical characteristics, antibacterial mechanism, pharmacokinetic properties and clinical significance are discussed. Particular attention is paid to the interaction of ciprofloxacin with bacterial DNA gyrase and topoisomerase IV, mechanisms of antimicrobial resistance, adverse reactions and restrictions on use. Based on scientific publications and official medical sources, the article also examines research into ciprofloxacin derivatives and the importance of responsible antimicrobial use.

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Published

2026-11-06

Issue

Vol. 4 No. 11 (2026): WOM

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

CIPROFLOXACIN: CHEMICAL STRUCTURE, MECHANISM OF ACTION, PHARMACOKINETICS AND CLINICAL SIGNIFICANCE. (2026). Web of Medicine: Journal of Medicine, Practice and Nursing , 4(11), 1-6. https://webofjournals.com/index.php/5/article/view/6819