THE EFFECT OF SUBSTANCES OBTAINED FROM THE PLANT LICIRICE (GLYCYRRHIZA glabra L) ON THE ORGANISM AND IMMUNE SYSTEM AFTER LIGHT THERAPY

Jakhongir Komilov; Mirtoza Allamuratov; Liliya Rashidova

Authors

Jakhongir Komilov National University of Uzbekistan named after Mirzo Ulugbek, Tashkent
Mirtoza Allamuratov National University of Uzbekistan named after Mirzo Ulugbek, Tashkent
Liliya Rashidova National University of Uzbekistan named after Mirzo Ulugbek, Tashkent

Keywords:

Licorice, Glycyrrhizic acid, Terabalt apparatus, Antibody, Antigen, biostimulant, Immunity, Polyoxidonium drug.

Abstract

Licorice root and its primary active component, glycyrrhizic acid, have long been studied for their therapeutic properties, including anti-inflammatory, antiviral, and hepatoprotective effects. This research investigates the effects of licorice root extract on the immune system, with a specific focus on its impact following radiation-induced secondary immunodeficiency. The study utilizes 25 male white red-eyed rats, which were exposed to light therapy using the Terabalt apparatus to induce immunodeficiency. Rats were divided into five groups, with varying treatments of glycyrrhizic acid solutions (0.01% and 0.03%) and Polyoxidonium, while a control group received no radiation. Antibody-producing cells, erythrocytes, and leukocytes were assessed post-treatment. Results indicated that glycyrrhizic acid significantly influenced the proliferation of T- and B-lymphocytes, highlighting its potential as a biostimulant to enhance immune function. These findings suggest that licorice root extract can play a crucial role in mitigating the adverse effects of radiation therapy and promoting immune recovery.